What Does It Do And Ought to You Begin Taking It?

What Is Glutamine | Glutamine Benefits | Popular Products | FAQ | Supplements With Glutamine | Side Effects And Warnings | Disclaimer

Glutamine is among the important amino acids that our physique must perform correctly. It’s a non-essential amino acid, that means our physique can produce it by itself. Nonetheless, sure situations, corresponding to intense train, sickness, or harm, could improve the demand for glutamine. On this weblog submit, we are going to take a better have a look at what glutamine is, why it will be important, and the way it can profit our our bodies.

Section Divider: What Is Glutamine

Glutamine is a sort of amino acid that’s generally present in our our bodies. It’s categorised as a non-essential amino acid, that means our physique can produce it independently. It’s made up of the amino acids glutamic acid and ammonia, which mix to kind L-glutamine, the most typical type of glutamine present in our physique.

Glutamine is a vital constructing block of proteins, that are important for the expansion and restore of tissues, together with muscle tissues. Additionally it is concerned in a number of metabolic processes, corresponding to glucose manufacturing within the liver and the regulation of acid-base stability within the physique. Though our physique can produce glutamine, sure situations, corresponding to intense train, sickness, or harm, can improve the demand for glutamine. Throughout these situations, our physique could also be unable to supply sufficient glutamine to satisfy the elevated demand, resulting in a deficiency. In such circumstances, glutamine supplementation could also be obligatory to take care of optimum well being. (1,2)

However, it’s additionally naturally present in meals like: (3)

  • Beef
  • Tofu
  • Eggs
  • Skim milk
  • White Rice
  • Corn

Section Divider: Glutamine Benefits

L Glutamine Advantages:

On this part, we’ll be going over what glutamine does and the advantages of supplementing with it!

  • Immune System
  • Intestine And Digestive Well being
  • Muscle Restoration
  • Coronary heart Well being

Glutamine And Your Immune System:

Glutamine performs a major function in selling your immunity by fueling immune cells like white blood cells. So naturally, when your physique is in a state of illness or harm, your want for glutamine can improve. Nonetheless, if the availability of glutamine is decrease than your physique’s wants, your physique could break down protein shops, corresponding to muscle. (3,4,5)


1. Anabolic, anticatabolic
2. Stimulates human development hormone launch
3. Acts as an Antioxidant
4. Direct gas for quickly dividing cells
5. Immune stimulant
6. Shuttle for ammonia
7. Synthesis for purine and pyrimidines

These properties of glutamine could help with decreasing the danger of wound an infection and will enhance the therapeutic of wounds. Although it might not dramatically impression the wound by itself. (3)

Glutamine And Intestine Well being:

Your intestinal well being is expounded to your immune system, aka intestine and digestive well being. That is most likely why you’re right here, so let’s begin by saying present analysis does assist the claims that glutamine may also help with intestine well being. (6) In case you didn’t know, there are trillions of fine micro organism in your intestines that make up your intestine flora. As a supply of power for intestinal and immune cells, glutamine may also help keep a barrier between your intestine and the remainder of your physique. This helps defend in opposition to leaky intestine and different pathogens that may result in sickness or irritation.  Present analysis additionally reveals that glutamine supplementation not solely helps barrier upkeep but additionally can enhance perform. (7)

Moreover, analysis suggests supplementation could profit gastrointestinal problems like inflammatory bowel illness (IBD) and irritable bowel syndrome (IBS). Nonetheless, various research point out that these advantages could also be restricted to remission occasions, not throughout flares. (8,9)

Does It Assist With Bloating?

As l-glutamine may also help with situations related to IBD and IBS, it might additionally assist cut back signs like: (8,9,10)

  • Bloating†
  • Constipation†
  • Cramping†
  • and so on.

Nonetheless, extra analysis is critical to point out if supplementing with glutamine can profit people with out gastrointestinal problems.

 Muscle Restoration:

One among glutamine’s most well-known advantages is as an ergogenic assist. Whereas analysis on this profit can contradict, there’s analysis that helps glutamine’s means to stop muscle catabolism (breakdown) and cut back muscle soreness. (11,12) Nonetheless, analysis doesn’t at the moment point out this amino acid can instantly promote energy or muscle development. And several other research counsel that it essentially boosts efficiency, regardless of decreasing fatigue. (13)

Coronary heart Well being:

New research are rising which counsel l glutamine could also be helpful for cardiovascular well being and illness. Resulting from its potent antioxidant and anti inflammatory properties, glutamine could assist cut back threat components for cardiovascular ailments like hypertension. (14)

Section Divider: Popular Products

Standard Merchandise:

Right here we’ll record some standard l-glutamine merchandise and how one can take them!

Optimum Nutrition Glutamine

How To Take Optimum Nutrition Glutamine:

Caps: The manufacturer recommends taking 1-2 capsules 30-45 minutes before workouts and/or immediately after workouts.

Powder: The manufacturer recommends mixing one (1) rounded teaspoon (5g) with 8oz water or your favorite beverage.

Customer Review By Andrew: “This is a great product. I have been taking it for years and feel its helped me maintain my results throughout fitness and health journey.”

AllMax Nutrition Glutamine


How To Take AllMax Nutrition Glutamine:

The manufacturer recommends mixing one (1) rounded teaspoon (5g) in water or juice once daily. For training sessions and athletic events, take approximately 30 minutes prior to training and immediately after training to help prevent muscle tissue breakdown and aid muscle recovery. At times when you are not training, mix 1 rounded teaspoon (5g) in water or juice approximately 45-60 minutes prior to meals.

Customer Review By Gilmar: “First time a bought this Allmax Glutamine to help on my recovery. Very happy with the results!”

NOW Foods L-Glutamine

How To Take NOW Foods L-Glutamine (Veg Capsules):

The manufacturer recommends taking one (1) capsule 1 to 3 times daily, preferably between meals. Store in a cool, dry place after opening.

Customer Review By David: “I have more energy, as well as my relief from acid reflux. My sweet craving has also diminished. I’ve been taking L Glutamine for 5 weeks. I will be placing another order.”

Nutrex Glutamine Drive

How To Take Nutrex Glutamine Drive:

The manufacturer recommends mixing one (1) scoop with 6-8oz of water or any beverage of your choice. They also suggest taking two (2) servings daily; one in the morning upon rising and one before going to bed. On training days, you may want to take an extra serving following your workout.

Customer Review Gary: “Easy to mix, and great for recovery. A must for any serious lifter, or athlete.”

Section Divider: Glutamine FAQs

Glutamine FAQs:

In this section, we’re tackling some of your most frequently asked questions about l glutamine!

Glutamine VS Glutamate

Both glutamine and glutamate belong to the family of amino acids, the “glutamate family.” Where l glutamate is the most abundant free amino acid in the brain, but it is also a non-essential amino acid. This amino acid is the major excitatory neurotransmitter of the central nervous system. Through the synthesis of l glutamine and Kreb’s cycle intermediates, glutamic acid in the brain is formed. Here, glutamate plays a role in many neuronal functions, like synaptic maintenance and plasticity. (15)

Glutamine VS Glutamate Structure

Glutamine For Temper?

It’s doable, as some research counsel, that a rise within the glutamine–glutamate ratio could enhance temper and cognition. Nonetheless, different research’ outcomes counsel that the buildup of glutamine within the blood and mind can negatively have an effect on mind perform. Finally, extra analysis is critical to grasp the connection between glutamine and cognition/temper. (16,17)

Can It Assist With Weight Loss?

A pilot analysis research’s outcomes counsel that glutamine supplementation could enhance insulin sensitivity in sick sufferers and will improve glucose metabolism. Related outcomes have been present in a current research centered on chubby and overweight populations. These outcomes do counsel that glutamine supplementation could help with weight reduction. Nonetheless, extra analysis is critical to evaluate whether or not these outcomes are in line with various teams. (18,19,20)

Ought to You Stack It With Creatine?

Each creatine and glutamine could help with muscle restoration and promote efficiency. Nonetheless, the research on glutamine’s results on muscle development and efficiency will not be as clear as these with creatine. So whereas these dietary supplements could be a nice stack for some people, others could not get to expertise all of the potential advantages. (21,22)

Section Divider: Supplements With Glutamine

Dietary supplements With Glutamine:

In relation to amino acids, you’ve gotten the lucky alternative to get them from quite a lot of sources. Likewise, glutamine could be supplemented by itself or with different blends. On this part, we’re going to dive into some standard intra and post-workout dietary supplements that function glutamine. 

Formula 19 Supplement Facts

Our first post-workout supplement is Blackstone Lab’s Formula 19. Formula 19 features a recovery carbohydrate formula with four ingredients, including 9 grams of glutamine per serving.

R3 Carbohydrate Blend:

Current research studies support consuming carbohydrates post-workout as a way to replenish muscle glycogen stores. (23)


L-Leucine is our first ingredient aside of the branched-chain amino acids trio. This amino could contribute to protein synthesis and muscle restore. (24,25)

Magnesium Glycyl Glutamine:

Magnesium Glycyl-Glutamine may also help promote the restoration and anabolic advantages of glutamine with the improved metabolic processes from magnesium. (26)

How To Take Blackstone Labs Components 19:

The producer recommends males combine two (2) scoops in 8-10 oz. of water and take them post-workout on coaching days. Whereas girls combine one (1) scoop in 8-10 oz. of water and take it post-workout on coaching days.

Buyer Assessment By John: “Retains me powered up by my exercise, nice pumps and muscle fullness.”

alani nu bcaa Supplement FactsOur next featured product is Alani Nu BCAA. This formula features a simple 5-gram BCAA formula with only .5 grams of glutamine. Unfortunately, this is lower than most recommendations for glutamine, as it is often supplemented at doses between 5-30 grams. (28


Isoleucine is a part of the three branched-chain amino acids (BCAAs). It performs a job in muscle metabolism, together with constructing and repairing muscle. Isoleucine is a vital amino acid, so it’s worthwhile to eat it from meals or dietary supplements. The present advice of isoleucine for adults is round 13 mg every day. Nonetheless, for muscle development, it is not uncommon to see isoleucine in a BCAA complement dosed in a 2:1:1 ratio with leucine and valine. (29,24)


Valine is our final of the branched-chain amino acids and our final shared amino acid between the merchandise. And like the opposite two, valine helps stimulate muscle development, restore, and power manufacturing. (24,30)

How To Take Alani Nu BCAA:

The producers suggest mixing one (1) scoop per 8-10oz of water. Shake effectively for the most effective consistency and taste. This product is greatest consumed throughout train or in between meals.

Buyer Assessment By Michele: “Can’t do a exercise with out this! It’s a sport changer. Prevents me from being sore and I’ve a significantly better exercise! Completely adore it. And it’s scrumptious too!”

Xtend Supplement FactsNext, we have Scivation Xtend BCAA, one of our more popular BCAA supplements. This intra-workout supplement features 7 grams of BCAAs and 2.5 grams of glutamine. In addition to these ingredients, Xtend also features around 1.2 grams of electrolytes and 1 gram of citrulline malate.

Electrolyte Blend:

This blend of potassium and sodium can assist with maintaining hydration and promoting muscle repair. (31,32,33)

Citrulline Malate:

Citrulline Malate combines the nonessential amino acid L Citrulline and Malic Acid. This amino acid performs a job in bettering train efficiency and widening your blood vessels, which can assist in bettering muscle development. (34,35)

How To Take Scivation Xtend BCAA:

The producer recommends mixing two (2) scoops every day in 10-14 fl. oz. of water (alter for style desire) and shake effectively.

  • On coaching days: Combine one (1) scoop throughout train and one (1) scoop after train.
  • On non-training days: Combine two (2) scoops all through the day.

Buyer Assessment By Mathew: “Fruit Punch is our favourite, & it actually helps for exercises, simply can’t do with out it, however for some purpose unable discover the 90 servings domestically, so was joyful to seek out this retailer. It arrived shortly, which was nice since low on our current batch, so that is our go to provider going ahead.”

BCAA Optima Supplement FactsOur next BCAA matrix comes from NutraKey’s BCAA Optima. This formula features 7 grams of BCAAs like Xtend but with 100 mg more glutamine and 500 mg less of citrulline malate. However, unlike in Xtend, BCAA Optima also features Taurine in its electrolyte blend.


Taurine is an amino acid found commonly in the brain. It serves multiple purposes in the body including (36): 

  • Sustaining hydration and electrolytes
  • Regulates minerals corresponding to calcium
  • Helps the nervous system and eyes
  • Regulate immune system features

However, taurine additionally could increase train efficiency research counsel that taurine could assist in eradicating waste merchandise that result in fatigue and muscle burn. This interprets to it being efficient in selling endurance, rising alertness, and enhancing restoration. (37)

How To Take Nutrakey BCAA Optima:

The producers suggest mixing one (1) scoop with 8-12 oz. of water earlier than your exercise and one (1) scoop with 8-12 oz. of water an hour after your exercise. Nonetheless, you could need to alter the servings primarily based in your life-style. The producers suggest casual-light exercise take one (1) scoop post-workout. Whereas customers with a extra moderate-weekly exercise stage could need to take one (1) scoop post-workout and one (1) scoop earlier than mattress. Athletes could need to take one (1) scoop with a meal and one (1) scoop earlier than and after a exercise.

Buyer Assessment By Robert: “These BCAA’s are nice! Style nice and will get the job carried out. Extremely advisable!”

BCAA Supreme Supplement FactsAnd the last intra-post workout supplement in our list is BCAA Supreme from USP Labs. This formula features a proprietary blend, so we wouldn’t be able to compare each of the ingredients directly. In addition to BCAAs, BCAA Supreme also features L-Alanine, Taurine, Glycine, L-Lysine HCl, and L-Alanyl-L-Glutamine (aka Sustamine™).


Alanine or beta alanine is a popular ingredient for pre workouts, which is because beta alanine can help aid performance. This amino acid can help buffer away lactic acid build-up, which is associated with the “burn” effect of training a muscle. For these benefits, you would need around 2-5 grams of beta alanine. (38)


Along with being an amino acid, the physique makes use of glycine to make glutathione (an antioxidant) which is a element of creatine and collagen. This ingredient could assist improve cognitive perform, decrease blood stress, and will assist management blood glucose. (39)

L-Lysine HCl:

Lysine is one other amino acid that may play a job in protein synthesis. It additionally helps hormone and enzyme manufacturing and different features.  (24,40)


Sustamine™ is a mixture of two amino acids, L-glutamine and L-alanine. This mixture has potential protecting, absorption-enhancing actions and even inhibits muscle protein catabolism (muscle breakdown). (41

How To Take USP Labs BCAA Supreme:

The producers suggest mixing one (1) serving (2 stage scoops) in 20 ounces of water and shaking vigorously for 30 seconds. Sip all through a exercise, athletic occasion, or any time extra amino acids are wanted. Resulting from excessive leucine content material, some preliminary foaming could happen, which ought to subside over a couple of minutes with mild shaking. Shake the container earlier than every use to disperse substances that will have settled.

Buyer Assessment By Jacob: “Simply bought it right this moment. Rocket Pop taste tastes nice. Powder mixes effectively.”

Section Divider: Final Thoughts

Wrapping Up!

And this marks the tip of our submit on Glutamine. Thanks for studying! And as all the time, if there was one thing that wasn’t clear, one other query you may need, or you probably have one other concept for a weblog, E-mail Us!

Are you in search of extra to learn? Take a look at our different blogs!

Section Divider: Side Effects And Warnings

Aspect Results And Warnings:

Don’t exceed advisable every day dose. Seek the advice of a doctor prior to make use of you probably have any medical situations. Meant just for adults 18 years and older. Not to be used by those that are pregnant, making an attempt to turn into pregnant, or nursing.

Section Divider: Disclaimer


†Please notice the intention of the data supplied is for reference solely. Moreover, we’re under no circumstances offering medical recommendation or instruction. As a substitute, the data supplied on this information/weblog makes use of anecdotal data and out there research/critiques. Whereas we goal to take care of and show correct data, we will’t assure it represents the newest product formulation or data. Subsequently, please go to the producer’s web site you probably have any considerations. Additionally, the data above doesn’t characterize our views right here at Similar Day Dietary supplements. As a substitute, these are the producers’ and customers’ views and data. Moreover, the Meals and Drug Administration has not evaluated these statements. Lastly, these merchandise goal to not diagnose, deal with, treatment, or forestall illness or sickness.